Effect of childhood maltreatment and brain-derived neurotrophic factor on brain morphology

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Effect of childhood maltreatment and brain-derived neurotrophic factor on brain morphology

Childhood maltreatment (CM) has been associated with altered brain morphology, which may partly be due to a direct impact on neural growth, e.g. through the brain-derived neurotrophic factor (BDNF) pathway. Findings on CM, BDNF and brain volume are inconsistent and have never accounted for the entire BDNF pathway. We examined the effects of CM, BDNF (genotype, gene expression and protein level)...

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Action of brain-derived neurotrophic factor on function and morphology of visual cortical neurons

Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...

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Action of brain-derived neurotrophic factor on function and morphology of visual cortical neurons

Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...

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Effect of exercise training on saliva brain derived neurotrophic factor, catalase and vitamin c

  Background: The balance between production of Reactive Oxygen Species (ROS) and antioxidant defense in the body has important health implications. The aim of this study was to investigate the changes in salivary antioxidants: catalase, vitamin C and brain-derived neurotrophic factor (BDNF), in sedentary men at rest and after acute exhaustive exercise.   Methods: This randomi...

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Brain-derived neurotrophic factor:

Dekan Summary BDNF (brain-derived neurotrophic factor) plays an important role in neuronal survival, growth and maintenance of several neuronal systems, serves as neurotransmitter modulator and participates in plasticity important for learning and memory. BDNF is widely expressed in the CNS, beginning early in development and extending throughout life. In the mammalian brain, it is most abundan...

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ژورنال

عنوان ژورنال: Social Cognitive and Affective Neuroscience

سال: 2016

ISSN: 1749-5016,1749-5024

DOI: 10.1093/scan/nsw086